During the construction of luxury apartment buildings a huge nest of thousands of snakes is discovered. Francis Chang (the boss) refuses to delay the construction and orders to kill all the animals. He is repeated warned by his wife, who had some nightmares concerning him and the snakes. They do not manage to kill all snakes and so they take revenge on the construction workers and Francis Chang. Soon thousands of killer snakes under the lead of a giant Boa invades the building an kill all the new inhabitants. Even a snake master can't stop them.
The 5 Kao brothers, separated since childhood, are unaware that the master Teng Lung Manor, Lung Chen-feng has killed their father. All five, however, seek to defeat the vicious gangsters at the Manor.
Ivy Ling Po plays the dedicated wife of a man being blackmailed for an illicit love affair, who uncovers a pit of deceit, double-crosses, extortion and murder after murder.