A scientist invents a serum that keeps a dog's head alive after its body dies. When the scientist dies of a heart attack, his crazed assistant cuts off his head and, using the serum, keeps the doctor's head alive and forces it to help him on an experiment to give his hunchbacked nurse assistant a new body.
The multi-millionaire Eduard Schlüter takes part under the name Schulze in a raffle of his own Schlüter works and wins a stay at the Grand Hotel. Disguised as a poor swallower, he would like to study the reactions of the hotel staff and guests. As an assistant, he takes his reliable servant Johann with him. Once there, he makes friends and also has cause for annoyance when his daughter and the housekeeper arrive.
